# Medtronic Guardian 4 vs Senseonics Eversense E3: specs and price compared

A sourced, side-by-side comparison of the Medtronic Guardian 4 (Medtronic) and Senseonics Eversense E3 (Senseonics) among continuous glucose monitors. Medtronic Guardian 4 is the cheaper of the two at $2478.3.

## Side by side

| Spec | Medtronic Guardian 4 | Senseonics Eversense E3 |
| --- | --- | --- |
| US price | $2478.3 | $3309.69 |
| Brand | Medtronic | Senseonics |
| Released | 2023-04 | 2022-02 |
| Wear duration days | 7 | 180 |
| Warmup time hours | 2 | 24 |
| Reading interval min | 5 | 5 |
| Water resistance | Splash-resistant only; not rated for submersion | Sensor is water-resistant once implanted; the external transmitter is removable for bathing/showering |
| App platform | iOS & Android (Guardian Connect app); also displays on the MiniMed 780G pump | iOS & Android (Eversense NOW app) |
| Prescription required | Yes | Yes |
| Mard accuracy pct | 10.6 | 8.5 |
| Sensor size | 1.50 x 2.60 x 2.00 in | approx. 0.72 x 0.14 in (18.3 x 3.5 mm) implantable sensor |

## Key differences

- Wear duration days: Medtronic Guardian 4 7 vs Senseonics Eversense E3 180
- Warmup time hours: Medtronic Guardian 4 2 vs Senseonics Eversense E3 24
- Water resistance: Medtronic Guardian 4 Splash-resistant only; not rated for submersion vs Senseonics Eversense E3 Sensor is water-resistant once implanted; the external transmitter is removable for bathing/showering
- App platform: Medtronic Guardian 4 iOS & Android (Guardian Connect app); also displays on the MiniMed 780G pump vs Senseonics Eversense E3 iOS & Android (Eversense NOW app)
- Mard accuracy pct: Medtronic Guardian 4 10.6 vs Senseonics Eversense E3 8.5
- Sensor size: Medtronic Guardian 4 1.50 x 2.60 x 2.00 in vs Senseonics Eversense E3 approx. 0.72 x 0.14 in (18.3 x 3.5 mm) implantable sensor

## Sources

- Medtronic Guardian 4: https://consumerguide.diabetes.org/products/cgms/guardian-4-sensor-guardian-4-transmitter (consumerguide.diabetes.org, verified 2026-08-01)
- Senseonics Eversense E3: https://www.diabetesnet.com/diabetes-technology/meters-monitors/continuous-monitors/eversense-cgms/ (diabetesnet.com, verified 2026-08-01)

Canonical: https://frontdeskreview.com/gear/continuous-glucose-monitors/medtronic-guardian-4-vs-senseonics-eversense-e3/
Cite: Per The Front Desk Review, Medtronic Guardian 4 ($2478.3) vs Senseonics Eversense E3 ($3309.69) — sourced spec-by-spec comparison at https://frontdeskreview.com/gear/continuous-glucose-monitors/medtronic-guardian-4-vs-senseonics-eversense-e3/
License: CC BY 4.0.