# Medtronic Guardian 4 vs Sibionics GS3: specs and price compared

A sourced, side-by-side comparison of the Medtronic Guardian 4 (Medtronic) and Sibionics GS3 (Sibionics) among continuous glucose monitors.

## Side by side

| Spec | Medtronic Guardian 4 | Sibionics GS3 |
| --- | --- | --- |
| US price | $2478.3 | not published |
| Brand | Medtronic | Sibionics |
| Released | 2023-04 | — |
| Wear duration days | 7 | 14 |
| Warmup time hours | 2 | 1 |
| Reading interval min | 5 | 5 |
| Water resistance | Splash-resistant only; not rated for submersion | IP38 - water-resistant to 1 m for up to 1 hour |
| App platform | iOS & Android (Guardian Connect app); also displays on the MiniMed 780G pump | iOS & Android |
| Prescription required | Yes | No |
| Mard accuracy pct | 10.6 | 8.83 |
| Sensor size | 1.50 x 2.60 x 2.00 in | 24.8 x 17.8 x 2.9 mm (0.98 x 0.70 x 0.11 in), 1.5 g |

## Key differences

- Wear duration days: Medtronic Guardian 4 7 vs Sibionics GS3 14
- Warmup time hours: Medtronic Guardian 4 2 vs Sibionics GS3 1
- Water resistance: Medtronic Guardian 4 Splash-resistant only; not rated for submersion vs Sibionics GS3 IP38 - water-resistant to 1 m for up to 1 hour
- App platform: Medtronic Guardian 4 iOS & Android (Guardian Connect app); also displays on the MiniMed 780G pump vs Sibionics GS3 iOS & Android
- Prescription required: Medtronic Guardian 4 Yes vs Sibionics GS3 No
- Mard accuracy pct: Medtronic Guardian 4 10.6 vs Sibionics GS3 8.83
- Sensor size: Medtronic Guardian 4 1.50 x 2.60 x 2.00 in vs Sibionics GS3 24.8 x 17.8 x 2.9 mm (0.98 x 0.70 x 0.11 in), 1.5 g

## Sources

- Medtronic Guardian 4: https://consumerguide.diabetes.org/products/cgms/guardian-4-sensor-guardian-4-transmitter (consumerguide.diabetes.org, verified 2026-08-01)
- Sibionics GS3: https://www.sibionicscgm.com/products/sibionics-gs3-cgm-continuous-glucose-monitoring-system (sibionicscgm.com, verified 2026-08-01)

Canonical: https://frontdeskreview.com/gear/continuous-glucose-monitors/medtronic-guardian-4-vs-sibionics-gs3/
Cite: Per The Front Desk Review, Medtronic Guardian 4 ($2478.3) vs Sibionics GS3 (not published) — sourced spec-by-spec comparison at https://frontdeskreview.com/gear/continuous-glucose-monitors/medtronic-guardian-4-vs-sibionics-gs3/
License: CC BY 4.0.