Best Cold Email Outreach · head-to-head

Mailshake vs Reply.io

A sourced, side-by-side comparison for cold email outreach. Mailshake has the lower entry price. Every figure links to the vendor's own page and the date we captured it.

At a glance

  • Price: Mailshake $25/mo vs Reply.io $49/mo — Mailshake is cheaper to start.
  • Free tier: Mailshake No; Reply.io No.
  • HIPAA: Mailshake —; Reply.io —.

Side by side

MailshakeReply.io
Entry price$25/mo (Starter)$49/mo (Email Volume)
Free tierNoNo
HIPAA (BAA)
SOC 2
GDPR
Best forSmall sales teams wanting email + built-in calling in one toolSales teams wanting AI-driven SDR automation at scale

Sources — Mailshake: mailshake.com (verified 2026-06-14). Reply.io: getapp.com (verified 2026-06-14).

Key features

Mailshake: SHAKESpeare AI email writer with copy generation; Built-in power dialer with unlimited North American minutes (Sales Engagement+); Data Finder for prospect identification by role, location, company; Lead Catcher unified inbox with lead management workflows; Mail merge with A/B testing and deliverability optimization

Reply.io: AI SDR autopilot/copilot mode with AI-created ICP for autonomous outreach; Multichannel sequences: email, LinkedIn, calls, SMS in one workflow; Built-in B2B contact database with Findy Chrome extension; Email volume-based pricing (not per-seat) on entry plan; Whitelabel options for agencies

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