Is Mailshake or Reply.io cheaper?

Mailshake has the lower entry price — Mailshake starts at $25/mo and Reply.io at $49/mo.

Does Mailshake or Reply.io support HIPAA?

HIPAA support — Mailshake: —; Reply.io: —. Confirm current scope with the vendor.

Mailshake vs Reply.io

A sourced, side-by-side comparison for cold email outreach. Mailshake has the lower entry price. Every figure links to the vendor's own page and the date we captured it.

Mailshake has the lower entry price — Mailshake starts at $25/mo, Reply.io at $49/mo. Free tier: Mailshake No, Reply.io No. HIPAA: Mailshake —, Reply.io —.

As of 2026-06-14 · figures link to their source below

Side by side

Mailshake

$25/mo entry

Entry price$25/mo (Starter)

Free tierNo

HIPAA (BAA)—

SOC 2—

GDPR—

Best forSmall sales teams wanting email + built-in calling in one tool

Reply.io

$49/mo entry

Entry price$49/mo (Email Volume)

Free tierNo

HIPAA (BAA)—

SOC 2—

GDPR—

Best forSales teams wanting AI-driven SDR automation at scale

Sources — Mailshake: mailshake.com (verified 2026-06-14) · Reply.io: getapp.com (verified 2026-06-14)

Key features

Mailshake: SHAKESpeare AI email writer with copy generation; Built-in power dialer with unlimited North American minutes (Sales Engagement+); Data Finder for prospect identification by role, location, company; Lead Catcher unified inbox with lead management workflows; Mail merge with A/B testing and deliverability optimization

Reply.io: AI SDR autopilot/copilot mode with AI-created ICP for autonomous outreach; Multichannel sequences: email, LinkedIn, calls, SMS in one workflow; Built-in B2B contact database with Findy Chrome extension; Email volume-based pricing (not per-seat) on entry plan; Whitelabel options for agencies

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