Is Mailshake or Reply.io cheaper?

Mailshake has the lower entry price — Mailshake starts at $29/mo and Reply.io at $49/mo.

Does Mailshake or Reply.io support HIPAA?

HIPAA support — Mailshake: —; Reply.io: —. Confirm current scope with the vendor.

Mailshake vs Reply.io

A sourced, side-by-side comparison for cold email outreach. Mailshake has the lower entry price. Every figure links to the public page it was captured from — the vendor's own wherever the vendor publishes the number, otherwise the named public source — with the date we captured it.

Mailshake has the lower entry price — Mailshake starts at $29/mo, Reply.io at $49/mo. Free tier: Mailshake No, Reply.io No. HIPAA: Mailshake —, Reply.io —.

As of 2026-09-05 · figures link to their source below

Side by side

Mailshake

$29/mo entry

Entry price$29/mo (Starter)

Free tierNo

HIPAA (BAA)—

SOC 2—

GDPR—

Best forSmall sales teams wanting email + built-in calling in one tool

Reply.io

$49/mo entry

Entry price$49/mo (Email Volume)

Free tierNo

HIPAA (BAA)—

SOC 2—

GDPR—

Best forSales teams wanting AI-driven SDR automation at scale

Sources — Mailshake: mailshake.com (verified 2026-09-02) · Reply.io: getapp.com (verified 2026-09-05)

Key features

Mailshake: SHAKESpeare AI email writer with copy generation; Built-in power dialer with unlimited North American minutes (Sales Engagement+); Data Finder for prospect identification by role, location, company; Lead Catcher unified inbox with lead management workflows; Mail merge with A/B testing and deliverability optimization

Reply.io: AI SDR autopilot/copilot mode with AI-created ICP for autonomous outreach; Multichannel sequences: email, LinkedIn, calls, SMS in one workflow; Built-in B2B contact database with Findy Chrome extension; Email volume-based pricing (not per-seat) on entry plan; Whitelabel options for agencies

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