Best Continuous Glucose Monitors · head-to-head

Medtronic Guardian 4 vs Sibionics GS3

A sourced, side-by-side comparison. Medtronic Guardian 4 is cheaper at $2478.3. Every spec and price links to its source.

Full spec sheet

marks the stronger figure where "more" — or "less", for price and weight — is unambiguously better.

Spec Medtronic Guardian 4 Sibionics GS3
US price $2478.3
BrandMedtronicSibionics
Released2023-04
Wear duration days 7 14
Warmup time hours 2 1
Reading interval min 5 5
Water resistance Splash-resistant only; not rated for submersion IP38 - water-resistant to 1 m for up to 1 hour
App platform iOS & Android (Guardian Connect app); also displays on the MiniMed 780G pump iOS & Android
Prescription required Yes No
Mard accuracy pct 10.6 8.83
Sensor size 1.50 x 2.60 x 2.00 in 24.8 x 17.8 x 2.9 mm (0.98 x 0.70 x 0.11 in), 1.5 g

Sources — Medtronic Guardian 4: consumerguide.diabetes.org (verified 2026-08-01). Sibionics GS3: sibionicscgm.com (verified 2026-08-01).

What's the difference between the Medtronic Guardian 4 and Sibionics GS3?

Where the two actually differ on the specs we track (7 of 8). Matching specs are omitted.

  • Wear duration days: Medtronic Guardian 4 7 vs Sibionics GS3 14
  • Warmup time hours: Medtronic Guardian 4 2 vs Sibionics GS3 1
  • Water resistance: Medtronic Guardian 4 Splash-resistant only; not rated for submersion vs Sibionics GS3 IP38 - water-resistant to 1 m for up to 1 hour
  • App platform: Medtronic Guardian 4 iOS & Android (Guardian Connect app); also displays on the MiniMed 780G pump vs Sibionics GS3 iOS & Android
  • Prescription required: Medtronic Guardian 4 true vs Sibionics GS3 false
  • Mard accuracy pct: Medtronic Guardian 4 10.6 vs Sibionics GS3 8.83
  • Sensor size: Medtronic Guardian 4 1.50 x 2.60 x 2.00 in vs Sibionics GS3 24.8 x 17.8 x 2.9 mm (0.98 x 0.70 x 0.11 in), 1.5 g

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